UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
发明人:
Jennifer Wu
申请号：
US14900510
公开号：
US09803017B2
申请日:
2014.07.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed are antibodies designed or selected to inhibit sMIC (e.g. to neutralize sMIC) shed from MIC+ tumors. Further disclosed are methods of using the antibodies for the treatment of MIC-positive cancers.
