This Hair is bright provide compound of formula I or its can Drug Yong Which, wherein R1, R2 and R3 illustrate that Books Suo Dings Righteousness. The bright It of this Hair be related to the method for the bright compound of this Hair of what System Prepare and its control Treatment purposes. The Drug Wu Group that mono- step of this Hair Ming Jin provides the bright compound of this Hair closes object and Drug reason activity Elixirs He the bright compound Group of this Hair is closed.本發明提供了式I化合物或其可藥用鹽,其中R1、R2和R3是說明書所定義的。本發明還涉及用於製備本發明化合物的方法,以及其治療用途。本發明進一步提供了本發明化合物的藥物組合物,以及藥理活性劑和本發明化合物的組合。