Refers to a Pharmaceutical composition comprising an Antibody anti CD38 and hyaluronidase.It also relates to a Pharmaceutical composition comprising an Antibody anti CD38 SEC with VH and VL. Id: 4 of sec.Id: 5 (1200 to 5000 mg), a rhuph20 hyaluronidase (30 000 to 45 000 u), histidine at a concentration of 5 mm to 15 mm sorbitol at a concentration of 100 mm to 300 mm, 20 PS at a concentration of 0.01% to 0.04% p \/ v P \/ V, and methionine at a concentration of 1mg \/ ml to 2mg \/ ml at a pH of 5.5, among others. These compositions are used for the treatment of cancer.Se refiere a una composicion farmaceutica que comprende un anticuerpo anti-CD38 y una hialuronidasa. Tambien se refiere a una composicion farmaceutica que comprende un anticuerpo anti-CD38 con VH de SEC No. ID: 4 y VL de SEC No. ID: 5 (1200 a 5000 mg), una hialuronidasa rHuPH20 (30 000 a 45 000 U), histidina a una concentracion de 5Mm a 15 Mm, sorbitol a una concentracion de 100 Mm a 300 Mm, PS-20 a una concentracion de 0,01% p/v a 0,04% p/v, y metionina a una concentracion de 1mg/ml a 2mg/ml a un pH de 5.5, entre otros. Dichas composiciones son usadas para el tratamiento del cancer.
