WILTZIUS, Jed,ALVAREZ RODRIGUEZ, Ruben,BELK, Jonathan
申请号:
EP17776833
公开号:
EP3436036A4
申请日:
2017.03.31
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The invention provides antibodies, antigen binding fragments thereof, chimeric antigen receptors (CARs), and engineered T cell receptors, polynucleotides encoding the same, and in vitro cells comprising the same. The polynucleotides, polypeptides, and in vitro cells described herein can be used in an engineered CAR T cell therapy for the treatment of a patient suffering from a cancer. In one embodiment, the polynucleotides, polypeptides, and in vitro cells described herein can be used for the treatment of multiple myeloma.