Olbrich, Carsten,Bunte, Thomas,Winter, Jonas,Peters, Jorg,Trill, Thomas
申请号:
AU2013343638
公开号:
AU2013343638A1
申请日:
2013.11.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
The present invention relates to stable pharmaceutical compositions which contain polypeptides having at least two antigen binding domains and are particularly suitable for subcutaneous administration. The invention provides liquid compositions which minimize the formation of unwanted polypeptide aggregates (dimers and/or multimers). The present invention further provides a method of minimizing the aggregation of polypeptides having antigen binding domains in liquid compositions.