Michael S. Roberts,Robert M. Lorence,William S. Groene,Harvey Rabin,Reid W. von Borstel
申请号：
US11698947
公开号：
US08105578B2
申请日:
2007.01.29
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The subject invention relates to viruses that are able to replicate and thereby kill neoplastic cells with a deficiency in the IFN-mediated antiviral response, and their use in treating neoplastic disease including cancer and large tumors. RNA and DNA viruses are useful in this regard. The invention also relates to methods for the selection, design, purification and use of such viruses for cancer therapy.
