HOENKE, CHRISTOPH,BERTANI, BARBARA,FERRARA, MARCO,FOSSATI, GIACOMO,FRATTINI, SARA,GIOVANNINI, RICCARDO,HOBSON, SCOTT
申请号：
CA3001929
公开号：
CA3001929A1
申请日:
2016.10.12
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The invention relates to Spirocyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide of general formula (I) which are inhibitors of phosphodiesterase 2, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
