Christoph Hoenke,Barbara Bertani,Marco Ferrara,Giacomo Fossati,Sara Frattini,Riccardo Giovannini,Scott Hobson
申请号:
US15291316
公开号:
US10023575B2
申请日:
2016.10.12
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention relates to Spirocyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxyamide of general formula (I) which are inhibitors of phosphodiesterase 2, useful in treating central nervous system diseases and other diseases.In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.