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СОСТАВЫ СОЕДИНЕНИЙ АЗАИНДОЛА
专利权人:
ВЕРТЕКС ФАРМАСЬЮТИКАЛЗ ИНКОРПОРЕЙТЕД (US)
发明人:
СИМОНЕ Эрик Артур (US),САНГХВИ Тапан (US),БАНДА Аламелу (US),СТАВРОПОУЛОС Кэтрин (US)
申请号:
RU2016122609
公开号:
RU2016122609A
申请日:
2014.11.12
申请国别(地区):
RU
年份:
2017
代理人:
摘要:
A pharmaceutical composition comprises: a) 5 wt % to 95 wt % of a HCl salt of Compound (1).xH2O by the weight of the pharmaceutical composition, wherein x is from 0 to 3 and b) 5 wt % to 95 wt % of a filler by the weight of the pharmaceutical composition. Another pharmaceutical composition comprises: a) 1 mg/mL to 20 mg/mL of Compound (1) in water and b) 0.01 M to 0.1 M of a pharmaceutically acceptable pH modifier. A method of preparing a pharmaceutical composition, comprising providing a mixture of Compound (1) that includes the HCl salt of Compound (1).xH2O and the filler. Another method of preparing a pharmaceutical composition comprises mixing the HCl salt of Compound (1).xH2O and the pH modifier to form 1 mg/mL to 20 mg/mL of Compound (1) in water. Methods of reducing the amount of influenza viruses, inhibiting the replication of influenza viruses, and treating influenza each independently employ such pharmaceutical compositions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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