TREATMENT OF OVARIAN CANCER USING AN ANTICANCER AGENT CONJUGATED TO AN ANGIOPEP-2 ANALOG

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专利权人:

ANGIOCHEM INC.

发明人:

CASTAIGNE, JEAN-PAUL,DEMEULE, MICHEL,LAWRENCE, BETTY

申请号：

CA2759129

公开号：

CA2759129C

申请日:

2010.04.20

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

Ovarian cancer is treated with conjugates of an anticancer agent and anAngiopep-2 polypeptide analog (i.e. apolypeptide comprising an ammo acid sequence at least 80% identical to Seq. IDNO:97). Such treatment includes utility in treatingmetastatic ovarian cancer and in treating patients who have previouslyexhibited resistance to standard chemotherapeuticagents. Preferred anticancer agents include taxanes while the preferredconjugate is ANG1005, a conjugate comprising threemolecules of paclitaxel conjugated to the peptide Angiopep-2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/