Richard David Semba,Luigi Ferruci,Edward G. Lakatta
申请号:
US14249451
公开号:
US20150051161A1
申请日:
2014.04.10
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compositions and methods for detecting carboxymethyl-lysine (CML) and circulating receptor for advanced glycation end (RAGE) products, and methods for correlating CML and RAGE levels with age-related disease. In particular, serum CML and/or circulating receptor for advanced glycation end (RAGE) products can be used as a clinical biomarker in diagnostics to identify people who are at a higher risk of developing adverse ageing-related outcomes.