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galenic formulation comprising aliskiren and process for its preparation by melt extrusion granulation
专利权人:
NOVARTIS AG
发明人:
INDRAJIT GHOSH,JAMES KOWALSKI,JENNIFER SNYDER,SUDHA VIPPAGUNTA,WEI-QIN TONG
申请号:
BRPI0919077
公开号:
BRPI0919077A2
申请日:
2009.09.23
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention relates to galenic formulations wherein the active ingredient aliskiren, preferably, a hemi-fumarate salt thereof, alone or in combination with another active ingredient, is melt-granulated and is present in an amount of more than 20% by weight based on the total weight of the oral dosage form, as well as a process of preparing said solid oral dosage form.
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