GALENICAL FORMULATION COMPRISING ALISKIREN AND PROCESS FOR ITS PREPARATION BY MELT EXTRUSION GRANULATION

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专利权人:

NOVARTIS AG

发明人:

GHOSH INDRAJIT,KOWALSKI JAMES,SNYDER JENNIFER,TONG WEI-QIN,VIPPAGUNTA SUDHA

申请号：

ZA201101686

公开号：

ZA201101686B

申请日:

2011.03.04

申请国别(地区):

ZA

年份:

2012

代理人:

摘要：

The present invention relates to galenic formulations wherein the active ingredient aliskiren, preferably, a hemi-fumarate salt thereof, alone or in combination with another active ingredient, is melt-granulated and is present in an amount of more than 20% by weight based on the total weight of the oral dosage form, as well as a process of preparing said solid oral dosage form.

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