Christopher Thomas Halsall,Laurent Francois Andre Hennequin,Alleyn Thomas Plowright,Richard Storey,Kieran Lennon
申请号：
US11884923
公开号：
US08735410B2
申请日:
2006.02.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention concerns quinazoline derivatives of the Formula I, or pharmaceutically acceptable salts thereof:wherein each of R1, R2, R3, R4 and m are as defined in the description processes for their preparation pharmaceutical compositions containing them and their use in the manufacture of a medicament for providing an anti-proliferative effect. The quinazoline derivatives of Formula I are expected to be useful in the treatment of diseases such as certain cancers mediated by erbB receptor tyrosine kinases, and, for example, EGFR tyrosine kinase.
