The present invention discloses a composition for lowering blood lipid and elevating high-density lipoprotein and a method for manufacturing the same the composition comprises monascin or ankaflavin, or a combination thereof the manufacturing method comprises the steps of: treating a Monascus fermented product with acetone for three times elevating the concentration of the Monascus fermented product by a process of decompress concentration and extracting the monascin and the ankaflavin from the Monascus fermented product with a silica gel column chromatography, a Sephadex LH-20 column chromatography, the silica gel column chromatography, and a preparative high performance liquid chromatography sequentially.
