PEPTIDE IMMUNISANT, PROCÉDÉ DE PRODUCTION DE PEPTIDE IMMUNISANT, COMPOSITION PHARMACEUTIQUE LE CONTENANT ET CIBLANT LES TROUBLES DE L'IMMUNITÉ ET PROCÉDÉ DE TRAITEMENT DE TROUBLES DE L'IMMUNITÉ
The present invention provides an immunizing peptide that can induce production of an antibody to a complex of the immunizing peptide and an MHC molecule of a living organism. The immunizing peptide according to the present invention includes a T-cell epitope and an antibody-inducing portion of a target protein. The antibody-inducing portion is at least one of the following amino acid residues in an amino acid sequence of the target protein: one or more contiguous amino acid residues immediately upstream of a N-terminal amino acid residue of the T-cell epitope； and one or more contiguous amino acid residues immediately downstream of a C-terminal amino acid residue of the T-cell epitope. When the immunizing peptide is administered to a living organism, the immunizing peptide induces production of an antibody to a complex of the immunizing peptide and an MHC molecule of the living organism.
