PEPTIDE IMMUNISANT, PROCÉDÉ DE FABRICATION DU PEPTIDE IMMUNISANT, COMPOSITION PHARMACEUTIQUE CONTENANT CELUI-CI ET CIBLANT LES TROUBLES DE L'IMMUNITÉ, ET MÉTHODE DE TRAITEMENT DE TROUBLES DE L'IMMUNITÉ
The present invention provides a novel immunizing peptide that can induce production of an antibody to a complex of the immunizing peptide and an MHC molecule of a living organism. The immunizing peptide according to the present invention includes a T-cell epitope and an antibody-inducing portion of a target protein. The antibody-inducing portion is at least one of the following amino acid residues in an amino acid sequence of the target protein: one or more contiguous amino acid residues immediately upstream of a N-terminal amino acid residue of the T-cell epitope； and one or more contiguous amino acid residues immediately downstream of a C-terminal amino acid residue of the T-cell epitope. When the immunizing peptide is administered to a living organism, the immunizing peptide induces production of an antibody to a complex of the immunizing peptide and an MHC molecule of the living organism.
