POURKAVOOS, NAZANEEN,NEY, JAMES R.,CRUANES, MARIA T.,WU, YUNHUI,PALKAR, SAURABH A.
申请号：
CA2588445
公开号：
CA2588445C
申请日:
2005.12.02
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
Pharmaceutical formulations suitable for oral administration in solid dosageforms are described. The compositions comprise an effective amount of a basesalt of a compound of Formula (I) and a release rate controlling compositioncomprising a solubilizing agent, a gelling agent, and a water soluble filler；wherein R1, R2, R3 and R4 are defined herein. The formulations are suitablefor use in the inhibition of HIV integrase, the treatment and prophylaxis ofHIV infection, and the treatment, prophylaxis and delay in the onset of AIDS.
