Nazaneen Pourkavoos,James R. Ney,Maria T. Cruanes,Yunhui Wu,Saurabh A. Palkar
申请号：
US11792118
公开号：
US08852632B2
申请日:
2005.12.02
申请国别(地区):
US
年份:
2014
代理人:
摘要：
Pharmaceutical formulations suitable for oral administration in solid dosage forms are described. The compositions comprise an effective amount of a base salt of a compound of Formula (I) and a release rate controlling composition comprising a solubilizing agent, a gelling agent, and a water soluble filler wherein R1, R2, R3 and R4 are defined herein. The formulations are suitable for use in the inhibition of HIV integrase, the treatment and prophylaxis of HIV infection, and the treatment, prophylaxis and delay in the onset of AIDS.
