The manner which detects inflammation Characteristic fault making use of the IL 1 isoform is offered. It offers also the manner which deals with inflammation Characteristic fault making use of the anti- IL 1 antibody. It offers also the manner which deals with inflammation Characteristic fault making use of at least one inside the anti- IL 1 antibody, and the anti- IL 22 antibody, the anti- IL 17 antibody or the anti- TNF antibody. < Figure 1 1 >IL-1アイソフォームを用いて炎症性障害を検出する方法を提供する。抗IL-1抗体を用いて炎症性障害を処置する方法も提供する。抗IL-1抗体、および抗IL-22抗体、抗IL-17抗体、または抗TNFα抗体のうちの少なくとも1つを用いて炎症性障害を処置する方法も提供する。【図1-1】