PROBLEM TO BE SOLVED: To provide pharmaceutical compositions for treating human patients having metastatic cancer that has progressed after treatment with chemotherapy, radiotherapy or biologic agents.SOLUTION: A composition is a polyclonal antibody being an immunoglobulin (Ig), a solution of identical or heterogeneous Igs, or a mixture of Igs which specifically binds interleukin-1α, and is administered to a subject by subcutaneous, intravenous or intramuscular injection, or direct injection into a tumor.SELECTED DRAWING: None【課題】化学療法、放射線療法又は生物学的薬剤での治療後に進行した転移性癌を有するヒト患者を治療するための医薬組成物の提供。【解決手段】インターロイキン－１αに特異的に結合する免疫グロブリン（Ｉｇ）、同一又は異種Ｉｇの溶液又はＩｇの混合物であるポリクローナル抗体を皮下、静脈内、筋肉内注射又は腫瘍への直接注射によって対象に投与する組成物。【選択図】なし
