Kathrin Ines MÜHLHÖLZL-ODÖRFER,Elke HORSTKOTTE,Sabine WEITENSTEINER,Isabel SOLE FONT,Akif Emre TÜRELI
申请号：
US15556235
公开号：
US20180243217A1
申请日:
2016.03.11
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides nanoparticles comprising at least one boronic acid compound and at least one stabilizing agent for the at least one boronic acid compound and/or a reaction product of the at least one boronic acid compound and the at least one stabilizing agent, whereby the nanoparticles have a particle size of about 10 to about 1000 nm. The present invention also provides a pharmaceutical composition comprising these nanoparticles and a method for the preparation of these nanoparticles and the respective pharmaceutical compositions. In addition, the present invention provides nanoparticles and pharmaceutical compositions for the treatment of several disorders, especially multiple myeloma, preferably by parenteral administration.
