BERTELSEN, POUL EGON,OLSEN, PEDER MOHR,NIELSEN, CARSTEN MARTINI,TOLLESHAUG, MAGNUS WILHELM
申请号：
CA2644400
公开号：
CA2644400C
申请日:
2006.02.02
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
