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カルシウム含有組成物の製造のための速い湿式凝集方法
专利权人:
タケダ ニコメド エイエス
发明人:
ベルテルセン,ポール,エゴン,オルセン,ペダー モー,ニールセン,カルステン マルティニ,トレスハウグ,マグナス,ウィルヘルム
申请号:
JP2007553728
公开号:
JP5305374B2
申请日:
2006.02.02
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
The present invention relates to a novel process for the preparation of a granulate comprising a calcium-containing compound as an active substance. The method comprises a method for the preparation of a granulate comprising a calcium-containing compound as an active substance, the method comprising, i) feeding a granulation chamber with a composition comprising the calcium-containing compound, ii) wet-massing the composition with a granulation liquid optionally comprising a pharmaceutically acceptable binder for a time period of at the most 30 sec to obtain a wet granulate, iii) drying the thus obtained wet granulate. A granulate obtained by the present method is especially suitable in the preparation of solid dosage forms, in particular in the preparation of tablets.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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