A real-time physiological signal measurement and feedback system is suitable to be worn on a body part of an user for decreasing the noise of motion, and includes a sensor module, a signal processing module and a feedback platform. The sensor module includes a first magnetic unit having a light emitting diode and a second magnetic unit having a photo-detector. The light emitting diode illuminates a light beam passing through the body part and being received by the photo-detector so as to generate an electric signal when both of the first and the second magnetic units attract mutually to sandwich the body part. The signal processing module converts the electrical signal into a digital signal. The feedback platform processes the digital signal to generate a physiological parameter, and is used as a multi-function driving recorder. An alarm is triggered or not by the feedback platform according to the physiological parameter.