James John Crawford,Daniel Fred Ortwine,BinQing Wei,Wendy B. Young
申请号:
US15693022
公开号:
US10045983B2
申请日:
2017.08.31
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Heteroaryl pyridone and aza-pyridone compounds are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using heteroaryl pyridone and aza-pyridone compounds for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.