CRAWFORD, JAMES JOHN,ORTWINE, DANIEL FRED,WEI, BINQING,YOUNG, WENDY B.,Crawford, James John,Ortwine, Daniel Fred,Wei, BinQing,Young, Wendy B.
申请号：
HRP20151442
公开号：
HRP20151442T1
申请日:
2015.12.31
申请国别(地区):
HR
年份:
2016
代理人:
摘要：
Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X 1 , X 2 , and X 3 are N, and including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
