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Anticancer steroidal lactones unsaturated in position 7 (8)
专利权人:
PHARMA MAR S.A.
发明人:
REYES BENITEZ JOSE FERNANDO,FRANCESCH SOLLOSO ANDRES,CUEVAS MARCHANTE MARIA DEL CARMEN,FERNANDEZ RODRIGUEZ ROGELIO
申请号:
NZ60326111
公开号:
NZ603261A
申请日:
2011.04.26
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
The disclosure relates to a compound of general formula (I), wherein R1-R17 and the ------ line are as defined in the specification. Specific examples of these steroidal lactones were isolated from the organism Mycale (Aegogropila) crassissima and are given the names Aegomycin A - H. The disclosure also relates to pharmaceutical compositions comprising these compounds and their use in the treatment of cancer.
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