The disclosure relates to a compound of general formula (I), wherein R1-R17 and the ------ line are as defined in the specification. Specific examples of these steroidal lactones were isolated from the organism Mycale (Aegogropila) crassissima and are given the names Aegomycin A - H. The disclosure also relates to pharmaceutical compositions comprising these compounds and their use in the treatment of cancer.Сполука загальної формули І, де R-Rі лінія ---- приймають різні значення для застосування при лікуванні ракових пухлин.(I)