A fiber-optic probe for multi-modal characterization of a tissue. The fiber optic probe may comprise a first group of fibers associated with a first modality of light. The first group of fibers may comprise a first light delivery fiber and a first light collection fiber. The fiber optic probe may also comprise a second group of fibers associated with at least a second modality of light, the second group of fibers comprising a second light delivery fiber and a second light collection fiber； The fiber optic probe may also comprise a longpass filter positioned distal to the first group of fibers and a lens positioned distal to the filter. The fiber optic probe may also comprise. The fiber optic probe may include the second group of fibers bypassing the filter. The second group of fibers may bypass the filter.
