O'Dwyer, Michael Eamon Peter,ODwyer, Michael Eamon Peter
申请号：
AU2016300128
公开号：
AU2016300128A1
申请日:
2016.07.28
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
NK cells and NK cell lines are modified to increase cytotoxicity, wherein the cells and compositions thereof have a use in the treatment of cancer. Production of modified NK cells and NK cell lines is via genetic modification to remove checkpoint inhibitory receptor expression and/or add mutant (variant) TRAIL ligand expression.
