A single use safety retractable syringe (10) having a retractable needle (20)is disclosed. The syringe includes a hollow barrel (11), a plunger (13) whichslideably fits in the barrel, and a piston (13) which fits on the forepart ofthe plunger. The syringe also includes an actuator mechanism (14), which islocated in the forepart of the barrel. The actuator is able to be fittedthrough the open end of that forepart of the hollow barrel. The actuatormechanism has a stem (18) for supporting a needle hub (15). Means (24) areprovided on the end of the plunger to engage the actuator and cause it toretract with the needle upon completion of the injection.