Gary G. Leisk,Tim Jia-Ching Lo,Lei Li,Evangelia Bellas,David L. Kaplan
申请号：
US15273327
公开号：
US20170007738A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The inventions provided herein relate to compositions, methods, delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein can be injectable such that they can be placed in a tissue to be treated with a minimally-invasive procedure (e.g., by injection). In some embodiments, the composition described herein comprises a compressed silk fibroin matrix, which can expand upon injection into the tissue and retain its original expanded volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void, e.g., for tissue repair and/or augmentation, or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments, the compositions described herein can be used for soft tissue repair or augmentation.
