BELLAS EVANGELIA,MARRA KACEY,RUBIN J PETER,KAPLAN DAVID L
申请号:
IN4581/DELNP/2014
公开号:
IN2014DN04581A
申请日:
2014.06.05
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The inventions provided herein relate to compositions methods delivery devices and kits for repairing or augmenting a tissue in a subject. The compositions described herein are injectable such that they can be placed in a tissue to be treated with a minimally invasive procedure (e.g. by injection) and/or be molded flexibly into a tissue void of any shape and/or size. In some embodiments the composition described herein comprises a plurality of silk fibroin particles which can retain their original volume within the tissue for a period of time. The compositions can be used as a filler to replace a tissue void e.g. for tissue repair and/or augmentation or as a scaffold to support tissue regeneration and/or reconstruction. In some embodiments the compositions described herein can be used for soft tissue repair or augmentation.