Enhancing activity of CAR T cells by co-introducing a bispecific antibody

• 收藏
• 分享

专利权人:

The Trustees of the University of Pennsylvania

发明人:

June, Carl H.,Zhao, Yangbing,Liu, Xiaojun

申请号：

AU2013289971

公开号：

AU2013289971A1

申请日:

2013.07.12

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a T cell, genetically modified to express a chimeric antigen receptor (CAR), a bispecific antibody, or a combination thereof to a subject. The CAR and bispecific antibody of the invention can comprise a human antibody, a humanized antibody, or antigen-binding fragments thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/