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Enhancing Activity of CAR T Cells by Co-Introducing a Bispecific Antibody
专利权人:
The Trustees of the University of Pennsylvania
发明人:
Carl H. June,Yangbing Zhao,Xiaojun Liu
申请号:
US14410427
公开号:
US20150322169A1
申请日:
2013.07.12
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention provides compositions and methods for treating cancer in a human. The invention includes administering a T cell, genetically modified to express a chimeric antigen receptor (CAR), a bispecific antibody, or a combination thereof to a subject. The CAR and bispecific antibody of the invention can comprise a human antibody, a humanized antibody, or antigen-binding fragments thereof.
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中国工程科技知识中心
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