PROBLEM TO BE SOLVED: To provide a nerve fiber protective agent composition which effectively protects sensory nerve fibers from irritating factors other than the objects of evaluation in electrophysiological evaluation for irritating materials, and stably retains the thickness of a base line in measurement with the lapse of time, and an evaluation method and an evaluation system for irritating materials using the same.SOLUTION: The nerve fiber protective agent composition is substantially composed of an oily component, and in which viscosity (mPa s) at 25°C lies in the range of 500 to 500,000. The evaluation system and evaluation method use the same.COPYRIGHT: (C)2013,JPO&INPIT【課題】刺激性物質の電気生理学的評価において知覚神経線維を評価対象外の刺激要因から有効に保護し、経時的計測においてベースラインの太さを安定的に維持する神経線維保護剤組成物と、これを用いた刺激性物質の評価方法及び評価システムを提供する。【解決手段】実質的に油性成分からなり、25℃における粘度(mPa・s)が500~500,000の範囲内である神経線維保護剤組成物。これを用いた刺激性物質の評価方法及び評価システム。【選択図】図1