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Formulation of doxylamine and pyridoxine and/or metabolites or salts thereof
专利权人:
Duchesnay Inc.
发明人:
Manon Vranderick,Jean-Luc St-Onge,Christelle Gedeon,Michele Gallo,Éric Gervais
申请号:
US14228228
公开号:
US09089489B2
申请日:
2014.03.27
申请国别(地区):
US
年份:
2015
代理人:
摘要:
A dual release oral dosage system/dosage form comprising an immediate release component/composition and a delayed release component/composition is described. Each of the immediate release component/composition and delayed release component/composition comprises one or more of doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a metabolite thereof and/or a salt thereof, and one or more of pyridoxine, a salt thereof, a metabolite thereof and/or a salt of the metabolite. The dual release oral dosage system/dosage form exhibits an improved pharmacokinetic profile relative to the current Diclectin® formulation and is useful for example for the alleviation of the symptoms of nausea and vomiting, for example in the case of nausea and vomiting in pregnancy (NVP).
来源网站:
中国工程科技知识中心
来源网址:
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