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FORMULATION OF DOXYLAMINE AND PYRIDOXINE AND/OR METABOLITES OR SALTS THEREOF
专利权人:
DUCHESNAY INC.
发明人:
VRANDERICK, MANON,ST-ONGE, JEAN-LUC,GEDEON, CHRISTELLE,GALLO, MICHELE,GERVAIS, ÉRIC
申请号:
SG11201403931Y
公开号:
SG11201403931YA
申请日:
2013.02.18
申请国别(地区):
SG
年份:
2014
代理人:
摘要:
A dual release oral dosage system/dosage form comprising an immediate release component/composition and a delayed release component/composition is described. Each of the immediate release component/composition and delayed release component/composition comprises one or more of doxylamine, an analog thereof, a derivative thereof, a prodrug thereof, a metabolite thereof and/or a salt thereof, and one or more of pyridoxine, a salt thereof, a metabolite thereof and/or a salt of the metabolite. The dual release oral dosage system/dosage form exhibits an improved pharmacokinetic profile relative to the current Diclectin® formulation and is useful for example for the alleviation of the symptoms of nausea and vomiting, for example in the case of nausea and vomiting in pregnancy (NVP).
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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