Small molecules for the modulation of MCL-1 and methods of modulatiing cell death, cell division, cell differentiation and methods of treating disorders

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专利权人:

Inc.;Dana-Farber Cancer Institute

发明人:

Walensky, Loren D.,Stewart, Michelle L.,Cohen, Nicole

申请号：

AU2011210567

公开号：

AU2011210567A1

申请日:

2011.01.31

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

This invention relates to compounds which selectively bind to the survival protein MCL-1 with high affinity and selectivity, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for modulating MCL-1 activity and for treating hyperproliferative disorders, angiogenesis disorders, cell cycle regulation disorders, autophagy regulation disorders, inflammatory disorders, and/or infectious disorders and/or for enhancing cellular engraftment and/or wound repair, as a sole agent or in combination with other active ingredients.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/