COMPOSITIONS D'IMMUNOGLOBULINES ANTI-CD45 RADIO-MARQUÉES STABILISÉES

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专利权人:

Inc.;Actinium Pharmaceuticals

发明人:

DAVE, Kaushik, J.,SHARMA, Shubh, D.

申请号：

EP17763864

公开号：

EP3426305A4

申请日:

2017.03.07

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.

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