STABILIZED RADIOLABELED ANTI-CD45 IMMUNOGLOBULIN COMPOSITIONS

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专利权人:

Kaushik J. Dave;Shubh D. Sharma

发明人:

Kaushik J. Dave,Shubh D. Sharma

申请号：

US15603817

公开号：

US20170326259A1

申请日:

2017.05.24

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Compositions and methods are described for stabilizing a radio-iodinated monoclonal IgG antibody for up to 17 days against radiolytic decomposition. The stabilized radiolabeled murine antibody binding the CD45 antigen expressed on various forms of lymphomas is useful as a radio-therapeutic and diagnostic agent in the treatment of human malignancies of hematopoietic origin, including lymphomas.

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