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Protein constructs designed for targeting and lysis of cells
专利权人:
Jacques Henri Max Cohen
发明人:
Jacques Henri Max Cohen,Wael Mahmoud,Marcelle Tonye Libyh,Nathalie Godin,Annelise Gimenez,Thierry Tabary,Beatrice Donvito,Daniel Baty,Xavier Dervillez
申请号:
US12094877
公开号:
US08900592B2
申请日:
2006.11.23
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention relates to a protein construct, comprising (i) a targeting moiety that is capable of binding to a target cell, and (ii) an effector immunogenic moiety that is capable of triggering an existing, vaccine-induced or natural, immune response. The protein construct, that is preferably in the form of a heteromultimeric protein, is useful for redirecting an immune response that was pre-existing in a patient, toward an undesired target cell.
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