Heterocyclic compounds and methods of their use

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专利权人:

Novartis AG

发明人:

Thomas David McCarthy,Alan Naylor

申请号：

US14903166

公开号：

US09714224B2

申请日:

2014.07.08

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The present invention relates generally to compounds that are useful in antagonizing the angiotensin II type 2 (AT2) receptor. More particularly, the invention relates to substituted isoquinoline compounds and their use as AT2 receptor antagonists. Pharmaceutical compositions comprising the compounds and their use in modulating the AT2 receptor and therapies that require modulation of the AT2 receptor are described.

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