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preservation of biomaterial properties and storage methods
专利权人:
LIFELINE SCIENTIFIC; INC.
发明人:
KELVIN G. M. BROCKBANK
申请号:
BR112015008925
公开号:
BR112015008925A2
申请日:
2013.10.18
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
abstract described herein are enhanced compositions and methods for storing biomaterials. in certain aspects, these biomaterials include natural and engineered eukaryotic tissues. the methods described herein include storing these biomaterials in such a way that they do not prevent or prevent the loss of biomaterial properties (e.g., extracellular matrix integrity, cell viability, or a combination thereof) occurring either during storage or after removal of the biomaterial from storage. in certain aspects, these biomaterials will be stored in animal product-free solutions containing an agent that prevents or decreases the loss of extracellular matrix integrity. abstract of patent summary: "preservation of biomaterial properties and storage methods". Enhanced methods and compositions for storing biomaterials are described herein. In some respects, biomaterials include natural and artificial eukaryotic tissues. The methods described herein include storage of these biomaterials in order to reduce or prevent loss of biomaterial properties (e.g., extracellular matrix integrity, cell viability or a combination thereof) from occurring either during storage or after removal of the storage biomaterial. In some respects, biomaterials will be stored in non-animal solutions containing an agent that prevents or reduces loss of extracellular matrix integrity. 1/4abstract described herein are enhanced compositions and methods for storing biomaterials. in certain aspects, these biomaterials include natural and engineered eukaryotic tissues. the methods described herein include storing these biomaterials in such a manner that reduces or prevents the loss of biomaterial properties (e.g., extracellular matrix integrity, cell viability, or a combination thereof) occurring either during storage or after removal of the biomaterial from storage. in certain aspects, these biomaterials will be stored in animal product-free solutions containing an agent that prevents or reduces the loss of e
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