リベロマイシンＡまたはその合成中間体の製造法、スピロケタール環含有化合物の製造方法、並びに新規抗癌剤、抗真菌剤および骨疾患治療剤

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专利权人:

国立研究開発法人理化学研究所

发明人:

長田 裕之,高橋 俊二,川谷 誠,榊 佳之,豊田 敦

申请号：

JP20150237319

公开号：

JP6066439(B2)

申请日:

2015.12.04

申请国别(地区):

日本

年份:

2017

代理人:

摘要：

A bacterium belonging to the genus Streptomyces having an ability to produce reveromycin A or a synthetic intermediate thereof, the bacterium being modified so as to increase expression of revQ gene coding for the amino acid sequence of SEQ ID NO: 36 or an amino acid sequence having an identity of not less than 80% to SEQ ID NO: 36 as compared with a parent strain, thereby the above-mentioned production ability is increased as compared with the parent strain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/