A sorbent selected from a group of re- versed-phase liquid chromatography sorbents is pro- posed as a digestive tract detoxicant for vertebrates, said sorbent being a hydrophobizated matrix of polysilicic acid gel having the general approximate formula (H20 )v{(SiO- 2)x(OH)yR }w, in which the ratio of z/y varies from 79/21 to 1/99, where: v is the amount of water physically sorbed x is the number of silica atoms in the gel structure ? is the number of silanol groups in the structure and on the surface of the gel z is the number of aliphatic or aromatic substituents R is a hydrocarbon radical which is bound to a silicate base by the covalent bond Si-C, Si-O-C or Si-NX-C and is comprised of linear or branched alkyl or fluoroalkyl residues with 2 to 24 carbon atoms, containing from 1 to 4 isolated or ad- jacent double bonds, or of a cyclic substituent hav- ing the general formula Ar(CH 2)�-, in which Ar is an aromatic or alicyclic monocyclic or polycyclic sub- stituent with 6 to 24 carbon atoms, where the values of n are from 0 to 6 and the ratio of v/w is from 0 to 95. The proposed detoxicants exhibit a high degree of hydrophobicity and effectiveness and are easy to take.
