KOO, Song Hee,구송희,JANG, Seon Ho,장선호,SEO, In Yong,서인용,KIM, Chan,김찬,LEE, Seoung Hoon,이승훈,SO, Yun Mi,소윤미,LEE, Ji Hyun,이지현
申请号：
KRKR2017/005705
公开号：
WO2017/209521A1
申请日:
2017.05.31
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
Provided is a scaffold for cell culture or tissue engineering. The scaffold according to one embodiment of the present invention comprises a fiber web having a three-dimensional network structure and formed by including a biodegradable scaffold fiber. Therefore, cell proliferation rate and survival rate can be improved according to the provision of a microenvironment scaffold suitable for the migration, proliferation, and differentiation of the cells to be cultured. In addition, since the scaffold can be easily removed without physically/chemically stimulating the cells cultured in the scaffold, the recovery of the cultured cells is simple, and the scaffold can be transplanted in vivo while including the cultured cells. Moreover, the shape/structure of the cells to be cultured can be cultured similarly to those of actual animal bodies such that the cultured cells can be more suitably applied, for transplantation, to in vitro experimental models or animal bodies. Furthermore, as the scaffold according to one embodiment of the present invention is modified into a substance for helping the culturing/differentiation of cells, proliferation and survival of the cells can be more improved and the cells to be cultured can be easily implemented into a three-dimensional shape.La présente invention concerne un échafaudage pour la culture cellulaire ou l'ingénierie tissulaire. L'échafaudage selon l'un des modes de réalisation de la présente invention comprend une bande de fibres ayant une structure de réseau tridimensionnelle et formée par inclusion d'une fibre d'échafaudage biodégradable. Par conséquent, le taux de prolifération cellulaire et le taux de survie peuvent être améliorés en fournissant un échafaudage de microenvironnement adapté à la migration, la prolifération et la différenciation des cellules à cultiver. En outre, étant donné que l'échafaudage peut être facilement retiré sans stimuler physiquement/chimiquement les cellules cultivées dans l'échafaudage, la récupé
