University of Louisville Research Foundation; Inc.
发明人:
Balamurugan APPAKALAI,Stuart K. WILLIAMS
申请号：
US16609063
公开号：
US20200054685A1
申请日:
2018.04.27
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A tissue construct is provided that comprises a pancreas derived microvessel fragment and a pancreatic islet cell. The pancreas derived microvessel fragment and the pancreatic islet cell can be incorporated into a biocompatible medium. Tissue constructs can be comprised of other cells, such as stem cells, combined with the pancreas derived microvascular fragment. Methods for isolating microvessel fragments from a pancreas are also provided and include enzymatic digestion of pancreatic tissue and separation of microvessel fragments from endocrine and exocrine tissue. Methods for treating diabetes are further provided and include administration of the tissue constructs.
