Provided is the use of a botulinum toxin in the manufacture of a medicament for treating a patient suffering from a headache, wherein the medicament is to be used in a method comprising the step of administering the botulinum toxin to a nerve located within 1.5 cm of at least one suture line of the patients skull, wherein the suture line is selected from the group consisting of frontal suture, squamous suture, occipitomastoid suture, coronal suture, lambdoid suture and sagittal suture, wherein the administration alleviates at least one symptom of the headache, thereby treating the patient suffering from the headache